EFFECT OF CHRONIC POLYPHARMACY AND THE DRUG BURDEN INDEX (DBI) ON PHYSICAL FUNCTION IN AGED MICE

Increasing DBI (measure of patient’s total exposure to anticholinergics and sedatives) is associated with impaired physical function in observational studies of older adults. We aim to determine the effect of polypharmacy (use of ≥ 5 drugs) and increasing DBI on functional outcomes in aged mice. Fro...

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Publicat a:Innov Aging
Autors principals: Mach, J., Logan, C., Gemikonakli, G., Kane, A.E., Howlett, S.E., de Cabo, R., Le Couteur, D.G., Hilmer, S.N.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6184776/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.3216
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