EFFECT OF CHRONIC POLYPHARMACY AND THE DRUG BURDEN INDEX (DBI) ON PHYSICAL FUNCTION IN AGED MICE

Increasing DBI (measure of patient’s total exposure to anticholinergics and sedatives) is associated with impaired physical function in observational studies of older adults. We aim to determine the effect of polypharmacy (use of ≥ 5 drugs) and increasing DBI on functional outcomes in aged mice. Fro...

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Bibliografske podrobnosti
izdano v:Innov Aging
Main Authors: Mach, J., Logan, C., Gemikonakli, G., Kane, A.E., Howlett, S.E., de Cabo, R., Le Couteur, D.G., Hilmer, S.N.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6184776/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.3216
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