EFFECT OF CHRONIC POLYPHARMACY AND THE DRUG BURDEN INDEX (DBI) ON PHYSICAL FUNCTION IN AGED MICE

Increasing DBI (measure of patient’s total exposure to anticholinergics and sedatives) is associated with impaired physical function in observational studies of older adults. We aim to determine the effect of polypharmacy (use of ≥ 5 drugs) and increasing DBI on functional outcomes in aged mice. Fro...

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Bibliografiska uppgifter
I publikationen:Innov Aging
Huvudupphovsmän: Mach, J., Logan, C., Gemikonakli, G., Kane, A.E., Howlett, S.E., de Cabo, R., Le Couteur, D.G., Hilmer, S.N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2017
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Abstracts
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6184776/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.3216
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