EFFECT OF CHRONIC POLYPHARMACY AND THE DRUG BURDEN INDEX (DBI) ON MUSCLE FUNCTION AND STRUCTURE IN AGED MICE

Ageing, polypharmacy (≥ 5 different drugs) and increasing DBI (anticholinergic/sedative medication exposure) are associated with falls and impaired physical function. Preclinical ageing models can assess underlying mechanistic changes. We investigated whether chronic therapeutic drugs (polypharmacy...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Innov Aging
Main Authors: Gemikonakli, G, Mach, J, Tran, T, Howlett, S, deCabo, R, Le Couteur, D, Hilmer, S
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
Assuntos:
Abstracts
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6229948/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.369
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares