AGE-ASSOCIATED CHANGES IN SDF-1 TARGETING MIRNAS 29B-1-5P AND 141-3P ARE LINKED TO KYNURENINE LEVELS IN MSCS

We have identified a number of miRNAs that increase with age in human and murine bone marrow-derived mesenchymal stem cells (BMSCs). These miRNAs target a number of osteogenic gene families including the Stromal cell-derived factor-1 (SDF-1α /CXCL12) axis. Two of these SDF-1 targeting miRNAs are als...

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Publicado en:Innov Aging
Main Authors: Elmansi, A, Hussein, K, Fulzele, S, Shi, X, McGee-Lawrence, M, Hamrick, M, Isales, C, Hill, W
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6229643/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.360
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