AGE-RELATED INCREASE IN KYNURENINE LINKED TO DECREASED OSTEOGENESIS VIA REDUCED SDF-1 IN MESENCHYMAL STEM CELLS

Stromal cell-derived factor-1 (SDF-1α /CXCL12) is a member of the pro-inflammatory CXC chemokine family. Our group previously reported the role of SDF-1α in in-vitro osteogenic differentiation and in vivo bone formation. In addition, SDF-1α is an essential factor for migration and homing of bone mar...

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Publicado no:Innov Aging
Main Authors: Hussein, K, Elmansi, A, Volkman, B, Shi, X, McGee-Lawrence, M, Hamrick, M, Isales, C, Hill, W
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6229835/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.362
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