MicroRNA-141-3p Negatively Modulates SDF-1 Expression in Age-Dependent Pathophysiology of Human and Murine Bone Marrow Stromal Cells

Stromal cell-derived factor-1 (SDF-1 or CXCL12) is a cytokine secreted by cells including bone marrow stromal cells (BMSCs). SDF-1 plays a vital role in BMSC migration, survival, and differentiation. Our group previously reported the role of SDF-1 in osteogenic differentiation in vitro and bone form...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Periyasamy-Thandavan, Sudharsan, Burke, John, Mendhe, Bharati, Kondrikova, Galina, Kolhe, Ravindra, Hunter, Monte, Isales, Carlos M, Hamrick, Mark W, Hill, William D, Fulzele, Sadanand
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
The Journal of Gerontology: Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696713/
https://ncbi.nlm.nih.gov/pubmed/31505568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gly186
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