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SIRT4 IS A MITOCHONDRIAL REGULATOR OF METABOLISM AND LIFESPAN IN DROSOPHILA MELANOGASTER
Sirtuins are an evolutionarily conserved family of NAD+-dependent deacylases that control metabolism, stress response, genomic stability, and longevity. In mammals, three of these sirtuins (Sirt3, 4, and 5) are located in the mitochondrial, while the fruit fly Drosophila melanogaster has only a sing...
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| Izdano u: | Innov Aging |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6229463/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.345 |
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