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Mechanisms of Lifespan Extension by Sirt6 in Drosophila melanogaster

Sirt6 is a multifunctional enzyme that regulates numerous cellular processes connected to longevity. Overexpressing Sirt6 extends lifespan in mice, but the underlying cellular mechanisms are unclear. Here, we used the powerful genetic tools and short lifespan of Drosophila melanogaster to better und...

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Detalhes bibliográficos
Publicado no:Innov Aging
Main Authors: Taylor, Jackson, Wood, Jason, Finn, Matthew, Liu, Julianna, Mizerak, Evan, Gordon, Sarah, Hutfilz, Corinne, Helfand, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7742554/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.2617
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