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REGULATION OF LIFESPAN BY DSIRT6 IN DROSOPHILA MELANOGASTER
Sirtuins (SIRT1-7 in mammals) are a family of NAD+ dependent deacylases which regulate multiple cellular pathways involved in the aging process. SIRT6, in particular, has emerged as a key regulator of longevity, with roles in DNA repair, metabolism, and chromatin modification. Sirt6 knockout mice ar...
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| Publicado no: | Innov Aging |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6229599/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.344 |
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