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REGULATION OF LIFESPAN BY DSIRT6 IN DROSOPHILA MELANOGASTER

Sirtuins (SIRT1-7 in mammals) are a family of NAD+ dependent deacylases which regulate multiple cellular pathways involved in the aging process. SIRT6, in particular, has emerged as a key regulator of longevity, with roles in DNA repair, metabolism, and chromatin modification. Sirt6 knockout mice ar...

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Bibliografische gegevens
Gepubliceerd in:Innov Aging
Hoofdauteurs: Taylor, J, Wood, J, Chang, C, Finn, M, Liu, J, Kim, D, Helfand, S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6229599/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.344
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