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mTORC1 is a key mediator of RON-dependent breast cancer metastasis with therapeutic potential

Metastasis is the biggest challenge in treating breast cancer, and it kills >40,000 breast cancer patients annually in the US. Aberrant expression of the RON receptor tyrosine kinase in breast tumors correlates with poor prognosis and has been shown to promote metastasis. However, the molecular m...

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Pubblicato in:NPJ Breast Cancer
Autori principali: Faham, Najme, Zhao, Ling, Welm, Alana L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226524/
https://ncbi.nlm.nih.gov/pubmed/30456298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-018-0091-5
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