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Entropic allostery dominates the phosphorylation‐dependent regulation of Syk tyrosine kinase release from immunoreceptor tyrosine‐based activation motifs

Spleen tyrosine kinase (Syk) is an essential player in immune signaling through its ability to couple multiple classes of membrane immunoreceptors to intracellular signaling pathways. Ligand binding leads to the recruitment of Syk to a phosphorylated cytoplasmic region of the receptors called ITAM....

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Protein Sci
Asıl Yazarlar: Feng, Chao, Roy, Amitava, Post, Carol Beth
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley & Sons, Inc. 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225982/
https://ncbi.nlm.nih.gov/pubmed/30051939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3489
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