Differential Dephosphorylation of the FcRγ Immunoreceptor Tyrosine-based Activation Motif Tyrosines with Dissimilar Potential for Activating Syk

The cell surface-expressed γ chain of the high affinity receptor for IgE (FcεRI) can be phosphorylated on two tyrosine residues of the immunoreceptor tyrosine-based activation motif (ITAM), leading to recruitment and activation of spleen tyrosine kinase (Syk), a kinase that is essential for mast cel...

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Autores principales: Yamashita, Toshiyuki, Suzuki, Ryo, Backlund, Peter S., Yamashita, Yumi, Yergey, Alfred L., Rivera, Juan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568911/
https://ncbi.nlm.nih.gov/pubmed/18715866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802679200
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