Omega-3 polyunsaturated fatty acid attenuates traumatic brain injury-induced neuronal apoptosis by inducing autophagy through the upregulation of SIRT1-mediated deacetylation of Beclin-1

BACKGROUND: Enhancing autophagy after traumatic brain injury (TBI) may decrease the expression of neuronal apoptosis-related molecules. Autophagy-mediated neuronal survival is regulated by the sirtuin family of proteins (SIRT). Omega-3 polyunsaturated fatty acids (ω-3 PUFA) are known to have antioxi...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Neuroinflammation
Asıl Yazarlar: Chen, Xiangrong, Pan, Zhigang, Fang, Zhongning, Lin, Weibin, Wu, Shukai, Yang, Fuxing, Li, Yasong, Fu, Huangde, Gao, Hongzhi, Li, Shun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225685/
https://ncbi.nlm.nih.gov/pubmed/30409173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1345-8
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller