Sirt1-inducible deacetylation of p21 promotes cardiomyocyte proliferation

Inducing cardiomyocyte proliferation is a hopeful approach for cardiac regeneration following myocardial infarction. Previous studies have shown that p21 inhibits the cardiomyocyte proliferation and cardiac regeneration. Deacetylation of p21 by Sirt1 deacetylase may reduce p21 abundance and remove p...

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Bibliographic Details
Published in:Aging (Albany NY)
Main Authors: Li, Bing, Li, Mengsha, Li, Xinzhong, Li, Hairui, Lai, Yanxian, Huang, Senlin, He, Xiang, Si, Xiaoyun, Zheng, Hao, Liao, Wangjun, Liao, Yulin, Bin, Jianping
Format: Artigo
Language:Inglês
Published: Impact Journals 2019
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949046/
https://ncbi.nlm.nih.gov/pubmed/31881009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102587
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