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Use of E. coli Purine Nucleoside Phosphorylase in the Treatment of Solid Tumors
The selective expression of non-human genes in tumor tissue to activate non-toxic compounds (Gene Directed Prodrug Enzyme Therapy, GDEPT) is a novel strategy designed for killing tumor cells in patients with little or no systemic toxicity. Numerous non-human genes have been evaluated, but none have...
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| 出版年: | Curr Pharm Des |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6224313/ https://ncbi.nlm.nih.gov/pubmed/29119917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1381612823666171109101851 |
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