A high glucose diet induces autophagy in a HLH-30/TFEB-dependent manner and impairs the normal lifespan of C. elegans

A high-glucose diet (HGD) is associated with the development of metabolic diseases that decrease life expectancy, including obesity and type-2 diabetes (T2D); however, the mechanism through which a HGD does so is still unclear. Autophagy, an evolutionarily conserved mechanism, has been shown to prom...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Franco-Juárez, Berenice, Mejía-Martínez, Fanny, Moreno-Arriola, Elizabeth, Hernández-Vázquez, Alain, Gómez-Manzo, Saul, Marcial-Quino, Jaime, Arreguín-Espinosa, Roberto, Velázquez-Arellano, Antonio, Ortega-Cuellar, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224263/
https://ncbi.nlm.nih.gov/pubmed/30299269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101577
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