The MXL-3/SBP-1 Axis Is Responsible for Glucose-Dependent Fat Accumulation in C. elegans

Chronic exposure to elevated glucose levels leads to fatty acid accumulation, which promotes the development of metabolic diseases such as obesity and type 2 diabetes. MXL-3 is a conserved transcriptional factor that modulates the inhibition of lipolysis in Caenorhabditis elegans. However, the role...

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Vydáno v:Genes (Basel)
Hlavní autoři: Mejia-Martinez, Fanny, Franco-Juarez, Berenice, Moreno-Arriola, Elizabeth, Hernández-Vázquez, Alain, Martinez-Avila, Marco, Gómez-Manzo, Saul, Marcial-Quino, Jaime, Carvajal, Karla, Velazquez-Arellano, Antonio, Ortega-Cuellar, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704220/
https://ncbi.nlm.nih.gov/pubmed/29113111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes8110307
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