The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans

Autophagy is a cellular recycling process that has an important anti-aging role, but the underlying molecular mechanism is not well understood. The mammalian TFEB was recently shown to regulate multiple genes in the autophagy process. Here we show that the predicted TFEB orthologue HLH-30 regulates...

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Detalhes bibliográficos
Main Authors: Lapierre, Louis R., De Magalhaes Filho, C Daniel, McQuary, Philip R., Chu, Chu-Chiao, Visvikis, Orane, Chang, Jessica T., Gelino, Sara, Ong, Binnan, Davis, Andrew E., Irazoqui, Javier E., Dillin, Andrew, Hansen, Malene
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866206/
https://ncbi.nlm.nih.gov/pubmed/23925298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3267
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