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An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense

The mechanisms that tightly control the transcription of host defense genes have not been fully elucidated. We previously identified TFEB as a transcription factor important for host defense, but the mechanisms that regulate TFEB during infection remained unknown. We used C. elegans to discover a pa...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Najibi, Mehran, Labed, Sid Ahmed, Visvikis, Orane, Irazoqui, Javier Elbio
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880541/
https://ncbi.nlm.nih.gov/pubmed/27184844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.052
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