Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1

Integrin-signaling complexes play important roles in cytoskeletal organization and cell adhesion in many species. Components of the integrin-signaling complex have been linked to aging in both Caenorhabditis elegans and Drosophila melanogaster, but the mechanism underlying this function is unknown....

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Detalhes bibliográficos
Main Authors: Kumsta, Caroline, Ching, Tsui-Ting, Nishimura, Mayuko, Davis, Andrew E, Gelino, Sara, Catan, Hannah H, Yu, Xiaokun, Chu, Chu-Chiao, Ong, Binnan, Panowski, Siler H, Baird, Nathan, Bodmer, Rolf, Hsu, Ao-Lin, Hansen, Malene
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059541/
https://ncbi.nlm.nih.gov/pubmed/24314125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12189
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