Histone variant macroH2A1 rewires carbohydrate and lipid metabolism of hepatocellular carcinoma cells towards cancer stem cells

Hepatocellular carcinomas (HCCs) contain a sub-population of cancer stem cells (CSCs) that are responsible for tumor relapse, metastasis, and chemoresistance. We recently showed that loss of macroH2A1, a variant of the histone H2A and an epigenetic regulator of stem-cell function, in HCC leads to CS...

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Vydáno v:Epigenetics
Hlavní autoři: Lo Re, Oriana, Douet, Julien, Buschbeck, Marcus, Fusilli, Caterina, Pazienza, Valerio, Panebianco, Concetta, Castracani, Carlo Castruccio, Mazza, Tommaso, Li Volti, Giovanni, Vinciguerra, Manlio
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224214/
https://ncbi.nlm.nih.gov/pubmed/30165787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2018.1514239
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