טוען...
A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model
BACKGROUND: Alzheimer’s disease (AD) and related tauopathies are neurodegenerative diseases that are characterized by the presence of insoluble inclusions of the protein tau within brain neurons and often glia. Tau is normally found associated with axonal microtubules (MTs) in the brain, and in tauo...
שמור ב:
| הוצא לאור ב: | Mol Neurodegener |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BioMed Central
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6223064/ https://ncbi.nlm.nih.gov/pubmed/30404654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0291-3 |
| תגים: |
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