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Data-Driven Exploration of Selectivity and Off-Target Activities of Designated Chemical Probes

Chemical probes are of central relevance for chemical biology. To unambiguously explore the role of target proteins in triggering or mediating biological functions, small molecules used as probes should ideally be target-specific; at least, they should have sufficiently high selectivity for a primar...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Molecules
Egile Nagusiak: Miljković, Filip, Bajorath, Jürgen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222907/
https://ncbi.nlm.nih.gov/pubmed/30249057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23102434
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