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Data-Driven Exploration of Selectivity and Off-Target Activities of Designated Chemical Probes
Chemical probes are of central relevance for chemical biology. To unambiguously explore the role of target proteins in triggering or mediating biological functions, small molecules used as probes should ideally be target-specific; at least, they should have sufficiently high selectivity for a primar...
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| Published in: | Molecules |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6222907/ https://ncbi.nlm.nih.gov/pubmed/30249057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23102434 |
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