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Identifying Promiscuous Compounds with Activity against Different Target Classes

Compounds with multitarget activity are of high interest for polypharmacological drug discovery. Such promiscuous compounds might be active against closely related target proteins from the same family or against distantly related or unrelated targets. Compounds with activity against distinct targets...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Molecules
Κύριοι συγγραφείς: Feldmann, Christian, Miljković, Filip, Yonchev, Dimitar, Bajorath, Jürgen
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: MDPI 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891533/
https://ncbi.nlm.nih.gov/pubmed/31752252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24224185
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