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Identifying Promiscuous Compounds with Activity against Different Target Classes

Compounds with multitarget activity are of high interest for polypharmacological drug discovery. Such promiscuous compounds might be active against closely related target proteins from the same family or against distantly related or unrelated targets. Compounds with activity against distinct targets...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Feldmann, Christian, Miljković, Filip, Yonchev, Dimitar, Bajorath, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891533/
https://ncbi.nlm.nih.gov/pubmed/31752252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24224185
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