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A Bifunctional Anti-Amyloid Blocks Oxidative Stress and the Accumulation of Intraneuronal Amyloid-Beta

There is growing recognition regarding the role of intracellular amyloid beta (Aβ) in the Alzheimer’s disease process, which has been linked with aberrant signaling and the disruption of protein degradation mechanisms. Most notably, intraneuronal Aβ likely underlies the oxidative stress and mitochon...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Hilt, Silvia, Altman, Robin, Kálai, Tamás, Maezawa, Izumi, Gong, Qizhi, Wachsmann-Hogiu, Sebastian, Jin, Lee-Way, Voss, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222334/
https://ncbi.nlm.nih.gov/pubmed/30103547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23082010
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