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Protective spin-labeled fluorenes maintain amyloid beta peptide in small oligomers and limit transitions in secondary structure
Alzheimer’s disease is characterized by the presence of extracellular plaques comprised of amyloid beta (Aβ) peptides. Soluble oligomers of the Aβ peptide underlie a cascade of neuronal loss and dysfunction associated with Alzheimer’s disease. Single particle analyses of Aβ oligomers in solution by...
में बचाया:
में प्रकाशित: | Biochim Biophys Acta |
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मुख्य लेखकों: | , , , , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2015
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631661/ https://ncbi.nlm.nih.gov/pubmed/26374940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2015.09.002 |
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