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Protective spin-labeled fluorenes maintain amyloid beta peptide in small oligomers and limit transitions in secondary structure

Alzheimer’s disease is characterized by the presence of extracellular plaques comprised of amyloid beta (Aβ) peptides. Soluble oligomers of the Aβ peptide underlie a cascade of neuronal loss and dysfunction associated with Alzheimer’s disease. Single particle analyses of Aβ oligomers in solution by...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Biochim Biophys Acta
मुख्य लेखकों: Altman, Robin, Ly, Sonny, Hilt, Silvia, Petrlova, Jitka, Maezawa, Izumi, Kálai, Tamás, Hideg, Kálmán, Jin, Lee-Way, Laurence, Ted A., Voss, John C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631661/
https://ncbi.nlm.nih.gov/pubmed/26374940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2015.09.002
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