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Protective spin-labeled fluorenes maintain amyloid beta peptide in small oligomers and limit transitions in secondary structure
Alzheimer’s disease is characterized by the presence of extracellular plaques comprised of amyloid beta (Aβ) peptides. Soluble oligomers of the Aβ peptide underlie a cascade of neuronal loss and dysfunction associated with Alzheimer’s disease. Single particle analyses of Aβ oligomers in solution by...
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| Pubblicato in: | Biochim Biophys Acta |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631661/ https://ncbi.nlm.nih.gov/pubmed/26374940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2015.09.002 |
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