Role of Apolipoprotein L1 in Human Parietal Epithelial Cell Transition

Human parietal epithelial cells (PECs) are progenitor cells that sustain podocyte homeostasis. We hypothesized that the lack of apolipoprotein (APO) L1 ensures the PEC phenotype, but its induction initiates PEC transition (expression of podocyte markers). APOL1 expression and down-regulation of miR1...

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Publicado no:Am J Pathol
Main Authors: Kumar, Vinod, Vashistha, Himanshu, Lan, Xiqian, Chandel, Nirupama, Ayasolla, Kamesh, Shoshtari, Seyedeh Shadafarin Marashi, Aslam, Rukhsana, Paliwal, Nitpriya, Abbruscato, Frank, Mikulak, Joanna, Popik, Waldemar, Atta, Mohamed G., Chander, Praveen N., Malhotra, Ashwani, Meyer-Schwesinger, Catherine, Skorecki, Karl, Singhal, Pravin C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222279/
https://ncbi.nlm.nih.gov/pubmed/30201495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.07.025
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