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Renin modulates HIV replication in T cells

HIV is known to subvert cellular machinery to enhance its replication. Recently, HIV has been reported to enhance TC renin expression. We hypothesized that HIV induces and maintains high renin expression to promote its own replication in TCs. Renin enhanced HIV replication in TCs in a dose-dependent...

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Bibliographic Details
Main Authors: Chandel, Nirupama, Ayasolla, Kamesh, Lan, Xiqian, Rai, Partab, Mikulak, Joanna, Husain, Mohammad, Malhotra, Ashwani, McGowan, Joseph, Singhal, Pravin C.
Format: Artigo
Language:Inglês
Published: Society for Leukocyte Biology 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163631/
https://ncbi.nlm.nih.gov/pubmed/24970860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/JLB.2A0414-192R
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