mTOR plays a critical role in p53-induced oxidative kidney cell injury in HIVAN

Oxidative stress has been implicated to contribute to HIV-induced kidney cell injury; however, the role of p53, a modulator of oxidative stress, has not been evaluated in the development of HIV-associated nephropathy (HIVAN). We hypothesized that mammalian target of rapamycin (mTOR) may be critical...

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Bibliographic Details
Main Authors: Rai, Partab, Plagov, Andrei, Lan, Xiqian, Chandel, Nirupama, Singh, Tejinder, Lederman, Rivka, Ayasolla, Kamesh R., Mathieson, Peter W., Saleem, Moin A., Husain, Mohammad, Malhotra, Ashwani, Chander, Praveen N., Singhal, Pravin C.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742868/
https://ncbi.nlm.nih.gov/pubmed/23678040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00135.2013
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