Rapamycin-induced modulation of HIV gene transcription attenuates progression of HIVAN

HIV-associated nephropathy (HIVAN) is the manifestation of HIV genes expression by kidney cells in the presence of specific host factors. Recently, rapamycin (sirolimus) has been demonstrated to modulate the progression of HIVAN. We hypothesized that rapamycin would modulate the progression of HIVAN...

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Detalhes bibliográficos
Main Authors: Rai, Pratab, Plagov, Andrei, Kumar, Dileep, Pathak, Shresh, Ayasolla, Kamesh R., Chawla, Amrita, Mathieson, Peter W., Saleem, Moin A, Husain, Mohammad, Malhotra, Ashwani, Singhal, Pravin C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535680/
https://ncbi.nlm.nih.gov/pubmed/23010541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2012.09.009
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