Rapamycin-induced modulation of HIV gene transcription attenuates progression of HIVAN

HIV-associated nephropathy (HIVAN) is the manifestation of HIV genes expression by kidney cells in the presence of specific host factors. Recently, rapamycin (sirolimus) has been demonstrated to modulate the progression of HIVAN. We hypothesized that rapamycin would modulate the progression of HIVAN...

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Hlavní autoři: Rai, Pratab, Plagov, Andrei, Kumar, Dileep, Pathak, Shresh, Ayasolla, Kamesh R., Chawla, Amrita, Mathieson, Peter W., Saleem, Moin A, Husain, Mohammad, Malhotra, Ashwani, Singhal, Pravin C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535680/
https://ncbi.nlm.nih.gov/pubmed/23010541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2012.09.009
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