Modulation of apolipoprotein L1-microRNA-193a axis prevents podocyte dedifferentiation in high-glucose milieu

The loss of podocyte (PD) molecular phenotype is an important feature of diabetic podocytopathy. We hypothesized that high glucose (HG) induces dedifferentiation in differentiated podocytes (DPDs) through alterations in the apolipoprotein (APO) L1-microRNA (miR) 193a axis. HG-induced DPD dedifferent...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Mishra, Abheepsa, Ayasolla, Kamesh, Kumar, Vinod, Lan, Xiqian, Vashistha, Himanshu, Aslam, Rukhsana, Hussain, Ali, Chowdhary, Sheetal, Marashi Shoshtari, Shadafarin, Paliwal, Nitpriya, Popik, Waldemar, Saleem, Moin A., Malhotra, Ashwani, Meggs, Leonard G., Skorecki, Karl, Singhal, Pravin C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031922/
https://ncbi.nlm.nih.gov/pubmed/29357419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00541.2017
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