The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses

Infection with Citrobacter rodentium triggers robust tissue damage repair responses, manifested by secretion of IL-22, in the absence of which mice succumbed to the infection. Of the main hallmarks of C. rodentium infection are colonic crypt hyperplasia (CCH) and dysbiosis. In order to colonize the...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Berger, Cedric N., Crepin, Valerie F., Roumeliotis, Theodoros I., Wright, James C., Serafini, Nicolas, Pevsner-Fischer, Meirav, Yu, Lu, Elinav, Eran, Di Santo, James P., Choudhary, Jyoti S., Frankel, Gad
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221368/
https://ncbi.nlm.nih.gov/pubmed/30365535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007406
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