Citrobacter rodentium Subverts ATP Flux and Cholesterol Homeostasis in Intestinal Epithelial Cells In Vivo

The intestinal epithelial cells (IECs) that line the gut form a robust line of defense against ingested pathogens. We investigated the impact of infection with the enteric pathogen Citrobacter rodentium on mouse IEC metabolism using global proteomic and targeted metabolomics and lipidomics. The majo...

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Vydáno v:Cell Metab
Hlavní autoři: Berger, Cedric N., Crepin, Valerie F., Roumeliotis, Theodoros I., Wright, James C., Carson, Danielle, Pevsner-Fischer, Meirav, Furniss, R. Christopher D., Dougan, Gordon, Dori-Bachash, Mally, Yu, Lu, Clements, Abigail, Collins, James W., Elinav, Eran, Larrouy-Maumus, Gerald J., Choudhary, Jyoti S., Frankel, Gad
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695859/
https://ncbi.nlm.nih.gov/pubmed/28988824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.09.003
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