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Citrobacter rodentium Subverts ATP Flux and Cholesterol Homeostasis in Intestinal Epithelial Cells In Vivo

The intestinal epithelial cells (IECs) that line the gut form a robust line of defense against ingested pathogens. We investigated the impact of infection with the enteric pathogen Citrobacter rodentium on mouse IEC metabolism using global proteomic and targeted metabolomics and lipidomics. The majo...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Berger, Cedric N., Crepin, Valerie F., Roumeliotis, Theodoros I., Wright, James C., Carson, Danielle, Pevsner-Fischer, Meirav, Furniss, R. Christopher D., Dougan, Gordon, Dori-Bachash, Mally, Yu, Lu, Clements, Abigail, Collins, James W., Elinav, Eran, Larrouy-Maumus, Gerald J., Choudhary, Jyoti S., Frankel, Gad
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695859/
https://ncbi.nlm.nih.gov/pubmed/28988824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.09.003
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