Citrobacter rodentium Subverts ATP Flux and Cholesterol Homeostasis in Intestinal Epithelial Cells In Vivo

The intestinal epithelial cells (IECs) that line the gut form a robust line of defense against ingested pathogens. We investigated the impact of infection with the enteric pathogen Citrobacter rodentium on mouse IEC metabolism using global proteomic and targeted metabolomics and lipidomics. The majo...

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Gepubliceerd in:Cell Metab
Hoofdauteurs: Berger, Cedric N., Crepin, Valerie F., Roumeliotis, Theodoros I., Wright, James C., Carson, Danielle, Pevsner-Fischer, Meirav, Furniss, R. Christopher D., Dougan, Gordon, Dori-Bachash, Mally, Yu, Lu, Clements, Abigail, Collins, James W., Elinav, Eran, Larrouy-Maumus, Gerald J., Choudhary, Jyoti S., Frankel, Gad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695859/
https://ncbi.nlm.nih.gov/pubmed/28988824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.09.003
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