The type III secretion system effector EspO of enterohaemorrhagic Escherichia coli inhibits apoptosis through an interaction with HAX-1

Many enteric pathogens employ a type III secretion system (T3SS) to translocate effector proteins directly into the host cell cytoplasm, where they subvert signalling pathways of the intestinal epithelium. Here, we report that the anti-apoptotic regulator HS1-associated protein X1 (HAX-1) is an inte...

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Udgivet i:Cell Microbiol
Main Authors: Chatterjee, Sharanya, Lekmeechai, Sujinna, Constantinou, Nicolas, Grzybowska, Ewa A., Kozik, Zuzanna, Choudhary, Jyoti S., Berger, Cedric N., Frankel, Gad, Clements, Abigail
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613270/
https://ncbi.nlm.nih.gov/pubmed/34021690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.13366
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