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CXXC1 is not essential for normal DNA double-strand break formation and meiotic recombination in mouse

In most mammals, including mice and humans, meiotic recombination is determined by the meiosis specific histone methytransferase PRDM9, which binds to specific DNA sequences and trimethylates histone 3 at lysine-4 and lysine-36 at the adjacent nucleosomes. These actions ensure successful DNA double...

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Bibliografiska uppgifter
I publikationen:PLoS Genet
Huvudupphovsmän: Tian, Hui, Billings, Timothy, Petkov, Petko M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221362/
https://ncbi.nlm.nih.gov/pubmed/30365547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007657
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