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CXXC1 is not essential for normal DNA double-strand break formation and meiotic recombination in mouse

In most mammals, including mice and humans, meiotic recombination is determined by the meiosis specific histone methytransferase PRDM9, which binds to specific DNA sequences and trimethylates histone 3 at lysine-4 and lysine-36 at the adjacent nucleosomes. These actions ensure successful DNA double...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Tian, Hui, Billings, Timothy, Petkov, Petko M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221362/
https://ncbi.nlm.nih.gov/pubmed/30365547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007657
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