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CXXC1 is not essential for normal DNA double-strand break formation and meiotic recombination in mouse
In most mammals, including mice and humans, meiotic recombination is determined by the meiosis specific histone methytransferase PRDM9, which binds to specific DNA sequences and trimethylates histone 3 at lysine-4 and lysine-36 at the adjacent nucleosomes. These actions ensure successful DNA double...
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| Pubblicato in: | PLoS Genet |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6221362/ https://ncbi.nlm.nih.gov/pubmed/30365547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007657 |
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