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In vivo characterization of white matter pathology in premanifest huntington's disease

OBJECTIVE: Huntington's disease (HD) is a monogenic, fully penetrant neurodegenerative disorder, providing an ideal model for understanding brain changes occurring in the years prior to disease onset. Diffusion tensor imaging (DTI) studies show widespread white matter disorganization in the ear...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Zhang, Jiaying, Gregory, Sarah, Scahill, Rachael I., Durr, Alexandra, Thomas, David L., Lehericy, Stéphane, Rees, Geraint, Tabrizi, Sarah J., Zhang, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221120/
https://ncbi.nlm.nih.gov/pubmed/30063250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25309
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