In vivo characterization of white matter pathology in premanifest huntington's disease

OBJECTIVE: Huntington's disease (HD) is a monogenic, fully penetrant neurodegenerative disorder, providing an ideal model for understanding brain changes occurring in the years prior to disease onset. Diffusion tensor imaging (DTI) studies show widespread white matter disorganization in the ear...

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Enregistré dans:
Détails bibliographiques
Publié dans:Ann Neurol
Auteurs principaux: Zhang, Jiaying, Gregory, Sarah, Scahill, Rachael I., Durr, Alexandra, Thomas, David L., Lehericy, Stéphane, Rees, Geraint, Tabrizi, Sarah J., Zhang, Hui
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221120/
https://ncbi.nlm.nih.gov/pubmed/30063250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25309
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