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Miransertib (ARQ 092), an orally-available, selective Akt inhibitor is effective against Leishmania

Leishmaniasis is amongst the most important neglected diseases, afflicting more than 12 million people in 88 countries. There is an urgent need for safe orally bioavailable and cost-effective drugs for the treatment of leishmaniasis. It has recently been shown that Leishmania activates host macropha...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nandan, Devki, Zhang, Naixin, Yu, Yi, Schwartz, Brian, Chen, Stella, Kima, Peter E., Reiner, Neil E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219794/
https://ncbi.nlm.nih.gov/pubmed/30399177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206920
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