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In-vitro and in-vivo combined effect of ARQ 092, an AKT inhibitor, with ARQ 087, a FGFR inhibitor

The PI3K/AKT pathway plays an important role in the initiation and progression of cancer, and the drug development efforts targeting this pathway with therapeutic interventions have been advanced by academic and industrial groups. However, the clinical outcome is moderate. Combination of inhibition...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Anticancer Drugs
Κύριοι συγγραφείς: Yu, Yi, Hall, Terence, Eathiraj, Sudharshan, Wick, Michael J., Schwartz, Brian, Abbadessa, Giovanni
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Lippincott Williams & Wilkins 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404396/
https://ncbi.nlm.nih.gov/pubmed/28240679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0000000000000486
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