Preclinical Activity of ARQ 087, a Novel Inhibitor Targeting FGFR Dysregulation

Dysregulation of Fibroblast Growth Factor Receptor (FGFR) signaling through amplifications, mutations, and gene fusions has been implicated in a broad array of cancers (e.g. liver, gastric, ovarian, endometrial, and bladder). ARQ 087 is a novel, ATP competitive, small molecule, multi-kinase inhibito...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Hall, Terence G., Yu, Yi, Eathiraj, Sudharshan, Wang, Yunxia, Savage, Ronald E., Lapierre, Jean-Marc, Schwartz, Brian, Abbadessa, Giovanni
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023172/
https://ncbi.nlm.nih.gov/pubmed/27627808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162594
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы