Preclinical Activity of ARQ 087, a Novel Inhibitor Targeting FGFR Dysregulation

Dysregulation of Fibroblast Growth Factor Receptor (FGFR) signaling through amplifications, mutations, and gene fusions has been implicated in a broad array of cancers (e.g. liver, gastric, ovarian, endometrial, and bladder). ARQ 087 is a novel, ATP competitive, small molecule, multi-kinase inhibito...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Hall, Terence G., Yu, Yi, Eathiraj, Sudharshan, Wang, Yunxia, Savage, Ronald E., Lapierre, Jean-Marc, Schwartz, Brian, Abbadessa, Giovanni
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023172/
https://ncbi.nlm.nih.gov/pubmed/27627808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162594
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