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Treatment duration affects cytoprotective efficacy of positive allosteric modulation of α7nAChRs after focal ischemia in rats.

To minimize irreversible brain injury after acute ischemic stroke (AIS), the time to treatment (i.e., treatment delay) should be minimized. However, thus far, all cytoprotective clinical trials have failed. Analysis of literature identified short treatment durations (≤72 h) as a common motif among c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pharmacol Res
Egile Nagusiak: Gaidhani, Nikhil, Uteshev, Victor V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218269/
https://ncbi.nlm.nih.gov/pubmed/30205140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2018.09.001
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