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Treatment duration affects cytoprotective efficacy of positive allosteric modulation of α7nAChRs after focal ischemia in rats.
To minimize irreversible brain injury after acute ischemic stroke (AIS), the time to treatment (i.e., treatment delay) should be minimized. However, thus far, all cytoprotective clinical trials have failed. Analysis of literature identified short treatment durations (≤72 h) as a common motif among c...
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| Publicado no: | Pharmacol Res |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6218269/ https://ncbi.nlm.nih.gov/pubmed/30205140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2018.09.001 |
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