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PDTM-34. TARGETING H3.3G34R/V RE-WIRING OF THE EPIGENOME IN PAEDIATRIC GLIOBLASTOMA OF CHILDREN AND YOUNG ADULTS
Around 15% of cerebral hemispheric glioblastomas (GBM) of children and young adults harbour G34R/V mutations in H3F3A, encoding the histone H3.3 variant. These tumours have a peak incidence in late adolescence but are found up to 30yrs of age, and have conflicting data as to their prognosis compared...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217707/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.874 |
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