EXTH-54. Bcl-2/Bcl-xL INHIBITION SYNERGISTICALLY ENHANCES THE ANTI-NEOPLASTIC ACTIVITY OF CUSP9 AGAINST GLIOBLASTOMA CELLS IN VITRO

OBJECTIVE: Repurposing represents a promising approach to safely accelerate the clinical application of therapeutics with anti-cancer activity. In this study, we examined whether inhibition of the anti-apoptotic Bcl-2 family proteins Bcl-2 and Bcl-xL enhances the biological effects of the repurposed...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Halatsch, Marc-Eric, Kast, Richard Eric, Dwucet, Annika, Wirtz, Christian Rainer, Siegelin, Markus, Karpel-Massler, Georg
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217449/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.402
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