PDTM-06. ALK AMPLIFICATION AND REARRANGEMENTS ARE RECURRENT TARGETABLE EVENTS IN GLIOBLASTOMA

Anaplastic Lymphoma Kinase (ALK) expression, rearrangements, and single nucleotide variants have been reported in several brain tumor types, but the significance and function of each aberration in adults and children have not been clearly established. To determine the degree to which ALK represents...

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Vydáno v:Neuro Oncol
Hlavní autoři: Blandin, Anne-Florence, Graham, Maya, Ramkissoon, Shakti, Ramkissoon, Lori, Pelton, Kristine, Pages, Mélanie, Jones, Robert, Becker, Sarah, Watkinson, Fiona, Schoolcraft, Kathleen, Haemels, Veerle, Goumnerova, Liliana, Chi, Susan, Wright, Karen, Kieran, Mark, Tauziede-espariat, Arnault, Varlet, Pascale, Alexandrescu, Sanda, Reardon, David, Carcamo, Benjamin, Charest, Al, De Smet, Frederik, Beroukhim, Rameen, Dubuc, Adrian, Kittler, Ralf, Wen, Patrick, Alexander, Brian, Bandopadhayay, Pratiti, Bachoo, Robert, Ligon, Keith
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217201/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.848
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