PDTM-04. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES

While human tumors are shaped by the genetic evolution of cancer cells, evidence also suggests that they display superimposed hierarchies reminiscent of normal development. Yet, relating the genetic and hierarchical models of cancer organization has been limited by technical challenges. Here, studyi...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Filbin, Mariella, Tirosh, Itay, Hovestadt, Volker, Haberler, Christine, Pelton, Kristine, Czech, Thomas, Goumnerova, Liliana, Bandopadhayay, Pratiti, Louis, David, Kieran, Mark, Slavc, Irene, Ligon, Keith, Golub, Todd, Regev, Aviv, Bernstein, Bradley, Suva, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692941/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.769
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