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PDTM-04. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES

While human tumors are shaped by the genetic evolution of cancer cells, evidence also suggests that they display superimposed hierarchies reminiscent of normal development. Yet, relating the genetic and hierarchical models of cancer organization has been limited by technical challenges. Here, studyi...

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Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Filbin, Mariella, Tirosh, Itay, Hovestadt, Volker, Haberler, Christine, Pelton, Kristine, Czech, Thomas, Goumnerova, Liliana, Bandopadhayay, Pratiti, Louis, David, Kieran, Mark, Slavc, Irene, Ligon, Keith, Golub, Todd, Regev, Aviv, Bernstein, Bradley, Suva, Mario
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2017
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692941/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.769
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