PDTM-04. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES

While human tumors are shaped by the genetic evolution of cancer cells, evidence also suggests that they display superimposed hierarchies reminiscent of normal development. Yet, relating the genetic and hierarchical models of cancer organization has been limited by technical challenges. Here, studyi...

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Vydáno v:Neuro Oncol
Hlavní autoři: Filbin, Mariella, Tirosh, Itay, Hovestadt, Volker, Haberler, Christine, Pelton, Kristine, Czech, Thomas, Goumnerova, Liliana, Bandopadhayay, Pratiti, Louis, David, Kieran, Mark, Slavc, Irene, Ligon, Keith, Golub, Todd, Regev, Aviv, Bernstein, Bradley, Suva, Mario
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692941/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.769
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