PDTM-04. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES

While human tumors are shaped by the genetic evolution of cancer cells, evidence also suggests that they display superimposed hierarchies reminiscent of normal development. Yet, relating the genetic and hierarchical models of cancer organization has been limited by technical challenges. Here, studyi...

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Publicado en:Neuro Oncol
Autores principales: Filbin, Mariella, Tirosh, Itay, Hovestadt, Volker, Haberler, Christine, Pelton, Kristine, Czech, Thomas, Goumnerova, Liliana, Bandopadhayay, Pratiti, Louis, David, Kieran, Mark, Slavc, Irene, Ligon, Keith, Golub, Todd, Regev, Aviv, Bernstein, Bradley, Suva, Mario
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692941/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.769
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