DIPG-06. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES

While human tumors are shaped by the genetic evolution of cancer cells, evidence also suggests that they display superimposed hierarchies reminiscent of normal development. Yet, relating the genetic and hierarchical models of cancer organization has been limited by technical challenges. Here, studyi...

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Pubblicato in:Neuro Oncol
Autori principali: Filbin, Mariella G., Hovestadt, Volker, Tirosh, Itay, Shaw, McKenzie, Louis, David N., Slavc, Irene, Czech, Thomas, Pelton, Kristine, Goumnerova, Liliana, Bandopadhayay, Pratiti, Kieran, Mark W., Ligon, Keith, Golub, Todd, Bernstein, Brad, Regev, Aviv, Suva, Mario
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474977/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.021
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